2jrs

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[[Image:2jrs.jpg|left|200px]]
 
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{{Structure
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==Solution NMR Structure of CAPER RRM2 Domain. Northeast Structural Genomics Target HR4730A==
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|PDB= 2jrs |SIZE=350|CAPTION= <scene name='initialview01'>2jrs</scene>
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<StructureSection load='2jrs' size='340' side='right'caption='[[2jrs]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2jrs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JRS FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE= RBM39, HCC1, RNPC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jrs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jrs OCA], [https://pdbe.org/2jrs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jrs RCSB], [https://www.ebi.ac.uk/pdbsum/2jrs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jrs ProSAT], [https://www.topsan.org/Proteins/NESGC/2jrs TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=smart00360 RRM]</span>
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jrs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jrs OCA], [http://www.ebi.ac.uk/pdbsum/2jrs PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2jrs RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/RBM39_HUMAN RBM39_HUMAN] Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process.
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== Evolutionary Conservation ==
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'''Solution NMR Structure of CAPER RRM2 Domain. Northeast Structural Genomics Target HR4730A'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jr/2jrs_consurf.spt"</scriptWhenChecked>
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2JRS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JRS OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jrs ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Acton, T B.]]
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[[Category: Acton TB]]
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[[Category: Baran, M C.]]
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[[Category: Baran MC]]
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[[Category: Cunningham, K.]]
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[[Category: Cunningham K]]
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[[Category: Liu, J.]]
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[[Category: Liu J]]
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[[Category: Montelione, G T.]]
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[[Category: Montelione GT]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Nwosu C]]
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[[Category: Nwosu, C.]]
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[[Category: Owens L]]
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[[Category: Owens, L.]]
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[[Category: Rossi P]]
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[[Category: Rossi, P.]]
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[[Category: Rost B]]
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[[Category: Rost, B.]]
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[[Category: Swapna G]]
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[[Category: Swapna, G.]]
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[[Category: Xiao R]]
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[[Category: Xiao, R.]]
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[[Category: Zhao L]]
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[[Category: Zhao, L.]]
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[[Category: nesg]]
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[[Category: northeast structural genomics consortium]]
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[[Category: protein structure initiative]]
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[[Category: psi-2]]
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[[Category: rna binding motif of rbm39_human (caper)]]
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[[Category: rna binding protein]]
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[[Category: rrm2 domain]]
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[[Category: solution nmr structure]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:33:49 2008''
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Current revision

Solution NMR Structure of CAPER RRM2 Domain. Northeast Structural Genomics Target HR4730A

PDB ID 2jrs

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