5doi
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5doi is ON HOLD until Paper Publication Authors: Wan, B., Tang, T., Wu, J., Lei, M. Description: Crystal structure of Tetrahymena p45N and p19 [[Ca...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Tetrahymena p45N and p19== | |
| + | <StructureSection load='5doi' size='340' side='right'caption='[[5doi]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5doi]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DOI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DOI FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5doi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5doi OCA], [https://pdbe.org/5doi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5doi RCSB], [https://www.ebi.ac.uk/pdbsum/5doi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5doi ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TAP19_TETTS TAP19_TETTS] Component of a CST-like subcomplex of the holoenzyme telomerase ribonucleoprotein complex, which stimulates telomerase complementary-strand synthesis (PubMed:26551074). Telomerase is an essential ribonucleoprotein enzyme that copies new telomeric repeats onto chromosome ends by repetitively synthesizing the short telomere-repeat sequence 5'-TTGGGG-3' using an RNA template component TER (PubMed:26551074). The CST-like subcomplex (also named 7-4-1) binds telomeric single-stranded DNA and coordinates telomere G-strand and C-strand synthesis (PubMed:26551074).<ref>PMID:26551074</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[P19|P19]] | |
| - | + | *[[Telomerase-associated protein|Telomerase-associated protein]] | |
| - | [[Category: | + | == References == |
| - | [[Category: Lei | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Tetrahymena thermophila]] | ||
| + | [[Category: Lei M]] | ||
| + | [[Category: Tang T]] | ||
| + | [[Category: Wan B]] | ||
| + | [[Category: Wu J]] | ||
Current revision
Crystal structure of Tetrahymena p45N and p19
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