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2np3

From Proteopedia

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[[Image:2np3.gif|left|200px]]
 
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{{Structure
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==Crystal structure of TetR-family regulator (SCO0857) from Streptomyces coelicolor A3.==
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|PDB= 2np3 |SIZE=350|CAPTION= <scene name='initialview01'>2np3</scene>, resolution 2.35&Aring;
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<StructureSection load='2np3' size='340' side='right'caption='[[2np3]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[2np3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NP3 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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|GENE= SCO0857 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1902 Streptomyces coelicolor])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1309 AcrR], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00440 TetR_N]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2np3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2np3 OCA], [https://pdbe.org/2np3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2np3 RCSB], [https://www.ebi.ac.uk/pdbsum/2np3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2np3 ProSAT], [https://www.topsan.org/Proteins/MCSG/2np3 TOPSAN]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2np3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2np3 OCA], [http://www.ebi.ac.uk/pdbsum/2np3 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2np3 RCSB]</span>
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</table>
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}}
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== Function ==
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[https://www.uniprot.org/uniprot/Q9RCV4_STRCO Q9RCV4_STRCO]
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'''Crystal structure of TetR-family regulator (SCO0857) from Streptomyces coelicolor A3.'''
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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==About this Structure==
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<jmolCheckbox>
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2NP3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NP3 OCA].
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/np/2np3_consurf.spt"</scriptWhenChecked>
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[[Category: Single protein]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2np3 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptomyces coelicolor]]
[[Category: Streptomyces coelicolor]]
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[[Category: Chruszcz, M.]]
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[[Category: Chruszcz M]]
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[[Category: Cymborowski, M.]]
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[[Category: Cymborowski M]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Gu, J.]]
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[[Category: Gu J]]
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[[Category: Koclega, K D.]]
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[[Category: Joachimiak A]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Koclega KD]]
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[[Category: Minor, W.]]
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[[Category: Minor W]]
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[[Category: Savchenko, A.]]
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[[Category: Savchenko A]]
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[[Category: Xu, X.]]
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[[Category: Xu X]]
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[[Category: mcsg]]
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[[Category: midwest center for structural genomic]]
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[[Category: protein structure initiative]]
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[[Category: psi-2]]
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[[Category: structural genomic]]
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[[Category: tetr]]
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[[Category: transcriptional regulator]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:34:28 2008''
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Current revision

Crystal structure of TetR-family regulator (SCO0857) from Streptomyces coelicolor A3.

PDB ID 2np3

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