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2o3j

From Proteopedia

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[[Image:2o3j.gif|left|200px]]
 
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{{Structure
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==Structure of Caenorhabditis Elegans UDP-Glucose Dehydrogenase==
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|PDB= 2o3j |SIZE=350|CAPTION= <scene name='initialview01'>2o3j</scene>, resolution 1.88&Aring;
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<StructureSection load='2o3j' size='340' side='right'caption='[[2o3j]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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<table><tr><td colspan='2'>[[2o3j]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O3J FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-glucose_6-dehydrogenase UDP-glucose 6-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.22 1.1.1.22] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1004 Ugd], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00984 UDPG_MGDP_dh], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam03720 UDPG_MGDP_dh_C]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o3j OCA], [https://pdbe.org/2o3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o3j RCSB], [https://www.ebi.ac.uk/pdbsum/2o3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o3j ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2o3j TOPSAN]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o3j OCA], [http://www.ebi.ac.uk/pdbsum/2o3j PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2o3j RCSB]</span>
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</table>
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}}
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== Function ==
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[https://www.uniprot.org/uniprot/UGDH_CAEEL UGDH_CAEEL] Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.
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'''Structure of Caenorhabditis Elegans UDP-Glucose Dehydrogenase'''
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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==About this Structure==
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<jmolCheckbox>
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2O3J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3J OCA].
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o3/2o3j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o3j ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: UDP-glucose 6-dehydrogenase]]
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[[Category: Almo SC]]
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[[Category: Almo, S C.]]
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[[Category: Burley SK]]
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[[Category: Burley, S K.]]
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[[Category: Milst S]]
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[[Category: Milst, S.]]
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[[Category: Patskovsky Y]]
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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[[Category: Ramagopal U]]
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[[Category: Patskovsky, Y.]]
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[[Category: Shi W]]
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[[Category: Ramagopal, U.]]
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[[Category: Toro R]]
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[[Category: Shi, W.]]
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[[Category: Vidal M]]
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[[Category: Toro, R.]]
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[[Category: Wengerter BC]]
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[[Category: Vidal, M.]]
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[[Category: Zhan C]]
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[[Category: Wengerter, B C.]]
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[[Category: Zhang Y]]
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[[Category: Zhan, C.]]
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[[Category: Zhang, Y.]]
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[[Category: new york structural genomix research consortium]]
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[[Category: nysgxrc]]
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[[Category: protein structure initiative]]
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[[Category: psi-2]]
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[[Category: structural genomic]]
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[[Category: udp-glucose dehydrogenase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:35:51 2008''
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Current revision

Structure of Caenorhabditis Elegans UDP-Glucose Dehydrogenase

PDB ID 2o3j

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