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5aqc

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'''Unreleased structure'''
 
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The entry 5aqc is ON HOLD until Paper Publication
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==KstR, transcriptional repressor of cholesterol degradation in Mycobacterium tuberculosis, bound to the cholesterol coenzyme A derivative, (25R)-3-oxocholest-4-en-26-oyl-CoA.==
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<StructureSection load='5aqc' size='340' side='right'caption='[[5aqc]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
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Authors: Podust, L.M., Ouellet, H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5aqc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AQC FirstGlance]. <br>
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Description: KstR, transcriptional repressor of cholesterol degradation in Mycobacterium tuberculosis, bound to the cholesterol coenzyme A derivative, (25R)-3-oxocholest-4-en-26-oyl-CoA.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5JB:(25S)-3-OXOCHOLEST-4-EN-26-OYL-COA'>5JB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Ouellet, H]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aqc OCA], [https://pdbe.org/5aqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aqc RCSB], [https://www.ebi.ac.uk/pdbsum/5aqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aqc ProSAT]</span></td></tr>
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[[Category: Podust, L.M]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KSTR_MYCTU KSTR_MYCTU] Controls the expression of genes used for utilizing diverse lipids as energy sources.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Ouellet H]]
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[[Category: Podust LM]]

Current revision

KstR, transcriptional repressor of cholesterol degradation in Mycobacterium tuberculosis, bound to the cholesterol coenzyme A derivative, (25R)-3-oxocholest-4-en-26-oyl-CoA.

PDB ID 5aqc

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