5e1d

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: '''Unreleased structure''' The entry 5e1d is ON HOLD Authors: Dong, C., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC) Descript...)
Current revision (12:26, 6 March 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5e1d is ON HOLD
+
==NTMT1 in complex with YPKRIA peptide==
-
 
+
<StructureSection load='5e1d' size='340' side='right'caption='[[5e1d]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
-
Authors: Dong, C., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5e1d]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E1D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E1D FirstGlance]. <br>
-
Description: NTMT1 in complex with YPKRIA peptide
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-
[[Category: Min, J]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e1d OCA], [https://pdbe.org/5e1d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e1d RCSB], [https://www.ebi.ac.uk/pdbsum/5e1d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e1d ProSAT]</span></td></tr>
-
[[Category: Bountra, C]]
+
</table>
-
[[Category: Tempel, W]]
+
== Function ==
-
[[Category: Arrowsmith, C.H]]
+
[https://www.uniprot.org/uniprot/NTM1A_HUMAN NTM1A_HUMAN] Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.<ref>PMID:20481588</ref> <ref>PMID:20668449</ref> <ref>PMID:24090352</ref>
-
[[Category: Dong, C]]
+
== References ==
-
[[Category: Edwards, A.M]]
+
<references/>
-
[[Category: Structural Genomics Consortium (Sgc)]]
+
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Arrowsmith CH]]
 +
[[Category: Bountra C]]
 +
[[Category: Dong C]]
 +
[[Category: Edwards AM]]
 +
[[Category: Min J]]
 +
[[Category: Tempel W]]

Current revision

NTMT1 in complex with YPKRIA peptide

PDB ID 5e1d

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5e1d"
Personal tools