5e26

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m (Protected "5e26" [edit=sysop:move=sysop])
Current revision (06:10, 5 July 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5e26 is ON HOLD
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==Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate==
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<StructureSection load='5e26' size='340' side='right'caption='[[5e26]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5e26]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E26 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PAU:PANTOTHENOIC+ACID'>PAU</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e26 OCA], [https://pdbe.org/5e26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e26 RCSB], [https://www.ebi.ac.uk/pdbsum/5e26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e26 ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/PANK2_HUMAN PANK2_HUMAN] Atypical pantothenate kinase-associated neurodegeneration;Classic pantothenate kinase-associated neurodegeneration. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/PANK2_HUMAN PANK2_HUMAN] May be the master regulator of the CoA biosynthesis.
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Authors: DONG, A., LOPPNAU, P., RAVICHANDRAN, M., CHENG, C., TEMPEL, W., SEITOVA, A., HUTCHINSON, A., HONG, B.S., Bountra, C., Arrowsmith, C.H., Edwards, A.M., BROWN, P.J., Structural Genomics Consortium (SGC)
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==See Also==
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*[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]]
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Description: Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate
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__TOC__
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[[Category: Unreleased Structures]]
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</StructureSection>
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[[Category: Hutchinson, A]]
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[[Category: Homo sapiens]]
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[[Category: Dong, A]]
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[[Category: Large Structures]]
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[[Category: Ravichandran, M]]
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[[Category: Arrowsmith CH]]
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[[Category: Hong, B.S]]
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[[Category: BROWN PJ]]
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[[Category: Cheng, C]]
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[[Category: Bountra C]]
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[[Category: Bountra, C]]
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[[Category: CHENG C]]
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[[Category: Tempel, W]]
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[[Category: DONG A]]
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[[Category: Loppnau, P]]
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[[Category: Edwards AM]]
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[[Category: Arrowsmith, C.H]]
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[[Category: HONG BS]]
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[[Category: Seitova, A]]
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[[Category: HUTCHINSON A]]
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[[Category: Brown, P.J]]
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[[Category: LOPPNAU P]]
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[[Category: Edwards, A.M]]
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[[Category: RAVICHANDRAN M]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: SEITOVA A]]
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[[Category: TEMPEL W]]

Current revision

Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate

PDB ID 5e26

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