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2px7

From Proteopedia

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[[Image:2px7.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8==
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|PDB= 2px7 |SIZE=350|CAPTION= <scene name='initialview01'>2px7</scene>, resolution 2.200&Aring;
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<StructureSection load='2px7' size='340' side='right'caption='[[2px7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2px7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PX7 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_4-phosphate_cytidylyltransferase 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.60 2.7.7.60] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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|GENE= ispD, TTHA0171 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 Thermus thermophilus HB8])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2px7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2px7 OCA], [https://pdbe.org/2px7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2px7 RCSB], [https://www.ebi.ac.uk/pdbsum/2px7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2px7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2px7 TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK00155 ispD]</span>
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2px7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2px7 OCA], [http://www.ebi.ac.uk/pdbsum/2px7 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2px7 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/ISPD_THET8 ISPD_THET8] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/px/2px7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2px7 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8'''
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==See Also==
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*[[MEP cytidylyltransferase 3D structures|MEP cytidylyltransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2PX7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PX7 OCA].
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[[Category: Large Structures]]
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[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Single protein]]
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[[Category: Chang S-H]]
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[[Category: Thermus thermophilus hb8]]
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[[Category: Chen L]]
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[[Category: Chang, S-H.]]
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[[Category: Chen L-Q]]
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[[Category: Chen, L-Q.]]
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[[Category: Ebihara A]]
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[[Category: Chen, L.]]
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[[Category: Kuramitsu S]]
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[[Category: Ebihara, A.]]
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[[Category: Lee D]]
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[[Category: Kuramitsu, S.]]
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[[Category: Liu Z-J]]
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[[Category: Lee, D.]]
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[[Category: Nguyen D]]
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[[Category: Liu, Z-J.]]
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[[Category: Rose JP]]
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[[Category: Nguyen, D.]]
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[[Category: Shinkai A]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Tsukuda M]]
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[[Category: Rose, J P.]]
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[[Category: Wang B-C]]
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[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
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[[Category: Yokoyama S]]
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[[Category: Shinkai, A.]]
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[[Category: Tsukuda, M.]]
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[[Category: Wang, B-C.]]
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[[Category: Yokoyama, S.]]
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[[Category: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase]]
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[[Category: ispd]]
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[[Category: ispd_thet8]]
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[[Category: national project on protein structural and functional analyse]]
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[[Category: nppsfa]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: secsg]]
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[[Category: southeast collaboratory for structural genomic]]
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[[Category: structural genomic]]
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[[Category: ttha0171]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:40:43 2008''
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Current revision

Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8

PDB ID 2px7

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