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5cbm

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==Crystal structure of PfA-M17 with virtual ligand inhibitor==
==Crystal structure of PfA-M17 with virtual ligand inhibitor==
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<StructureSection load='5cbm' size='340' side='right' caption='[[5cbm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='5cbm' size='340' side='right'caption='[[5cbm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5cbm]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CBM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CBM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5cbm]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_Vietnam_Oak-Knoll_(FVO) Plasmodium falciparum Vietnam Oak-Knoll (FVO)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CBM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=4ZN:(2S)-2-{[(R)-[(R)-AMINO(PHENYL)METHYL](HYDROXY)PHOSPHORYL]METHYL}-4-METHYLPENTANOIC+ACID'>4ZN</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kqz|3kqz]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=4ZN:(2S)-2-{[(R)-[(R)-AMINO(PHENYL)METHYL](HYDROXY)PHOSPHORYL]METHYL}-4-METHYLPENTANOIC+ACID'>4ZN</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cbm OCA], [http://pdbe.org/5cbm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cbm RCSB], [http://www.ebi.ac.uk/pdbsum/5cbm PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cbm OCA], [https://pdbe.org/5cbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cbm RCSB], [https://www.ebi.ac.uk/pdbsum/5cbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cbm ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A024V0B1_PLAFA A0A024V0B1_PLAFA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5cbm" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5cbm" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Drinkwater, N]]
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[[Category: Large Structures]]
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[[Category: McGowan, S]]
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[[Category: Drinkwater N]]
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[[Category: Ruggeri, C]]
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[[Category: McGowan S]]
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[[Category: Hydrolase]]
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[[Category: Ruggeri C]]
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[[Category: Hydroxamic acid]]
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[[Category: Inhibitor]]
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[[Category: M17 leucyl-aminopeptidase]]
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[[Category: Protease]]
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Current revision

Crystal structure of PfA-M17 with virtual ligand inhibitor

PDB ID 5cbm

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