2qgn
From Proteopedia
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| - | [[Image:2qgn.jpg|left|200px]] | ||
| - | + | ==Crystal structure of tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.== | |
| - | + | <StructureSection load='2qgn' size='340' side='right'caption='[[2qgn]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2qgn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bachd Bachd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QGN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">miaA, BH2366 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 BACHD])</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/tRNA_dimethylallyltransferase tRNA dimethylallyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.75 2.5.1.75] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgn OCA], [https://pdbe.org/2qgn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qgn RCSB], [https://www.ebi.ac.uk/pdbsum/2qgn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qgn ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [[https://www.uniprot.org/uniprot/MIAA_BACHD MIAA_BACHD]] Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). | |
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | [[Category: | + | <jmolCheckbox> |
| - | [[Category: | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qg/2qgn_consurf.spt"</scriptWhenChecked> |
| - | [[Category: | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: Abashidze, M | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: Acton, T B | + | </jmolCheckbox> |
| - | [[Category: Baran, M C | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qgn ConSurf]. |
| - | [[Category: Cunningham, K | + | <div style="clear:both"></div> |
| - | [[Category: Forouhar, F | + | __TOC__ |
| - | [[Category: Hunt, J F | + | </StructureSection> |
| - | [[Category: Janjua, H | + | [[Category: Bachd]] |
| - | [[Category: Liu, J | + | [[Category: Large Structures]] |
| - | [[Category: Ma, L | + | [[Category: TRNA dimethylallyltransferase]] |
| - | [[Category: Montelione, G T | + | [[Category: Abashidze, M]] |
| - | [[Category: | + | [[Category: Acton, T B]] |
| - | [[Category: Neely, H | + | [[Category: Baran, M C]] |
| - | [[Category: Rost, B | + | [[Category: Cunningham, K]] |
| - | [[Category: Seetharaman, J | + | [[Category: Forouhar, F]] |
| - | [[Category: Shastry, R | + | [[Category: Hunt, J F]] |
| - | [[Category: Tong, L | + | [[Category: Janjua, H]] |
| - | [[Category: Xiao, R | + | [[Category: Liu, J]] |
| - | [[Category: | + | [[Category: Ma, L C]] |
| - | [[Category: | + | [[Category: Montelione, G T]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | + | [[Category: Neely, H]] | |
| - | [[Category: | + | [[Category: Rost, B]] |
| - | + | [[Category: Seetharaman, J]] | |
| - | + | [[Category: Shastry, R]] | |
| - | + | [[Category: Tong, L]] | |
| + | [[Category: Xiao, R]] | ||
| + | [[Category: Alpha-beta protein]] | ||
| + | [[Category: Nesg]] | ||
| + | [[Category: PSI, Protein structure initiative]] | ||
| + | [[Category: Transferase]] | ||
Current revision
Crystal structure of tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.
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Categories: Bachd | Large Structures | TRNA dimethylallyltransferase | Abashidze, M | Acton, T B | Baran, M C | Cunningham, K | Forouhar, F | Hunt, J F | Janjua, H | Liu, J | Ma, L C | Montelione, G T | Structural genomic | Neely, H | Rost, B | Seetharaman, J | Shastry, R | Tong, L | Xiao, R | Alpha-beta protein | Nesg | PSI, Protein structure initiative | Transferase
