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3cin

From Proteopedia

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(New page: 200px {{Structure |PDB= 3cin |SIZE=350|CAPTION= <scene name='initialview01'>3cin</scene>, resolution 1.700&Aring; |SITE= <scene name='pdbsite=AC1:Cl+Binding+Site+...)
Current revision (14:56, 20 September 2023) (edit) (undo)
 
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[[Image:3cin.jpg|left|200px]]
 
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{{Structure
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==CRYSTAL STRUCTURE OF A MYO-INOSITOL-1-PHOSPHATE SYNTHASE-RELATED PROTEIN (TM_1419) FROM THERMOTOGA MARITIMA MSB8 AT 1.70 A RESOLUTION==
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|PDB= 3cin |SIZE=350|CAPTION= <scene name='initialview01'>3cin</scene>, resolution 1.700&Aring;
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<StructureSection load='3cin' size='340' side='right'caption='[[3cin]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Cl+Binding+Site+For+Residue+A+383'>AC1</scene>, <scene name='pdbsite=AC2:Cl+Binding+Site+For+Residue+A+384'>AC2</scene>, <scene name='pdbsite=AC3:Cl+Binding+Site+For+Residue+A+385'>AC3</scene>, <scene name='pdbsite=AC4:Mg+Binding+Site+For+Residue+A+386'>AC4</scene> and <scene name='pdbsite=AC5:Nad+Binding+Site+For+Residue+A+400'>AC5</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
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<table><tr><td colspan='2'>[[3cin]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vjp 1vjp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CIN FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Inositol-3-phosphate_synthase Inositol-3-phosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.5.1.4 5.5.1.4] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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|GENE= TM1419, TM_1419 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 Thermotoga maritima MSB8])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam07994 NAD_binding_5], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1260 INO1]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cin OCA], [https://pdbe.org/3cin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cin RCSB], [https://www.ebi.ac.uk/pdbsum/3cin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cin ProSAT], [https://www.topsan.org/Proteins/JCSG/3cin TOPSAN]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cin OCA], [http://www.ebi.ac.uk/pdbsum/3cin PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=3cin RCSB]</span>
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</table>
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}}
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== Function ==
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[https://www.uniprot.org/uniprot/Q9X1D6_THEMA Q9X1D6_THEMA]
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'''Crystal structure of MYO-inositol-1-phosphate synthase-related protein (TM1419) from Thermotoga maritima at 1.70 A resolution'''
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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==About this Structure==
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<jmolCheckbox>
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3CIN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. This structure supersedes the now removed PDB entry 1VJP. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CIN OCA].
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ci/3cin_consurf.spt"</scriptWhenChecked>
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[[Category: Inositol-3-phosphate synthase]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Single protein]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Thermotoga maritima msb8]]
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</jmolCheckbox>
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cin ConSurf].
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[[Category: isomerase]]
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<div style="clear:both"></div>
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[[Category: jcsg]]
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__TOC__
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[[Category: joint center for structural genomic]]
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</StructureSection>
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[[Category: myo-inositol-1-phosphate synthase-related protein]]
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[[Category: Large Structures]]
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[[Category: protein structure initiative]]
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[[Category: Thermotoga maritima MSB8]]
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[[Category: psi]]
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[[Category: structural genomic]]
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[[Category: tm1419]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 09:29:28 2008''
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Current revision

CRYSTAL STRUCTURE OF A MYO-INOSITOL-1-PHOSPHATE SYNTHASE-RELATED PROTEIN (TM_1419) FROM THERMOTOGA MARITIMA MSB8 AT 1.70 A RESOLUTION

PDB ID 3cin

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