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5abk
From Proteopedia
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==Structure of the N-terminal domain of the metalloprotease PrtV from Vibrio cholerae== | ==Structure of the N-terminal domain of the metalloprotease PrtV from Vibrio cholerae== | ||
| - | <StructureSection load='5abk' size='340' side='right' caption='[[5abk | + | <StructureSection load='5abk' size='340' side='right'caption='[[5abk]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5abk]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ABK OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5abk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ABK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ABK FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5abk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5abk OCA], [https://pdbe.org/5abk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5abk RCSB], [https://www.ebi.ac.uk/pdbsum/5abk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5abk ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PRTV_VIBCH PRTV_VIBCH] Metalloprotease that exhibits a cytotoxic effect leading to cell death. In host tissues, it could play a role in pathogenesis by modulating the stability of the extracellular matrix components such as fibronectin and fibrinogen. Also able to cleave plasminogen.<ref>PMID:18479458</ref> <ref>PMID:24492010</ref> <ref>PMID:9371455</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
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[[Category: Vibrio cholerae]] | [[Category: Vibrio cholerae]] | ||
| + | [[Category: Edwin A]] | ||
| + | [[Category: Karlsson G]] | ||
| + | [[Category: Mayzel M]] | ||
| + | [[Category: Ohman A]] | ||
| + | [[Category: Persson C]] | ||
| + | [[Category: Sauer-Eriksson AE]] | ||
| + | [[Category: Wai SN]] | ||
Current revision
Structure of the N-terminal domain of the metalloprotease PrtV from Vibrio cholerae
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