This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3jbt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3jbt" [edit=sysop:move=sysop])
Current revision (08:43, 7 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 3jbt is ON HOLD
+
==Atomic structure of the Apaf-1 apoptosome==
 +
<SX load='3jbt' size='340' side='right' viewer='molstar' caption='[[3jbt]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3jbt]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JBT FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jbt OCA], [https://pdbe.org/3jbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jbt RCSB], [https://www.ebi.ac.uk/pdbsum/3jbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jbt ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/APAF_HUMAN APAF_HUMAN] Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.<ref>PMID:10393175</ref> <ref>PMID:12804598</ref>
-
Authors: Zhou, M., Li, Y., Hu, Q., Bai, X., Huang, W., Yan, C., Scheres, S.H.W., Shi, Y.
+
==See Also==
-
 
+
*[[Apoptotic protease-activating factor-1 3D structures|Apoptotic protease-activating factor-1 3D structures]]
-
Description: Atomic structure of the Apaf-1 apoptosome
+
== References ==
-
[[Category: Unreleased Structures]]
+
<references/>
-
[[Category: Huang, W]]
+
__TOC__
-
[[Category: Hu, Q]]
+
</SX>
-
[[Category: Bai, X]]
+
[[Category: Equus caballus]]
-
[[Category: Li, Y]]
+
[[Category: Homo sapiens]]
-
[[Category: Yan, C]]
+
[[Category: Large Structures]]
-
[[Category: Scheres, S.H.W]]
+
[[Category: Bai X]]
-
[[Category: Zhou, M]]
+
[[Category: Hu Q]]
-
[[Category: Shi, Y]]
+
[[Category: Huang W]]
 +
[[Category: Li Y]]
 +
[[Category: Scheres SHW]]
 +
[[Category: Shi Y]]
 +
[[Category: Yan C]]
 +
[[Category: Zhou M]]

Current revision

Atomic structure of the Apaf-1 apoptosome

3jbt, resolution 3.80Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3jbt"
Personal tools