5e6t
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of bovine norovirus P domain== | |
| + | <StructureSection load='5e6t' size='340' side='right'caption='[[5e6t]], [[Resolution|resolution]] 2.27Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5e6t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Norovirus_Bo/GIII/B309/2003/BEL Norovirus Bo/GIII/B309/2003/BEL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E6T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E6T FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e6t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e6t OCA], [https://pdbe.org/5e6t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e6t RCSB], [https://www.ebi.ac.uk/pdbsum/5e6t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e6t ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/E6Y5B1_9CALI E6Y5B1_9CALI] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | We determined a structure of a bovine (genogroup III, GIII) norovirus capsid protruding (P) domain using X-ray crystallography. The bovine P domain was reminiscent of other norovirus genogroups (GI, GII, GIV, and GV), but closely matched the human GI P domain. We also identified a monoclonal antibody that was capable of binding the five different (GI-GV) P domains. Our data suggests that genetically diverse noroviruses still contain common epitopes. | ||
| - | + | Structural analysis of bovine norovirus protruding domain.,Singh BK, Koromyslova A, Hansman GS Virology. 2015 Nov 17;487:296-301. doi: 10.1016/j.virol.2015.10.022. PMID:26599362<ref>PMID:26599362</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: Hansman | + | <div class="pdbe-citations 5e6t" style="background-color:#fffaf0;"></div> |
| - | [[Category: Singh | + | |
| + | ==See Also== | ||
| + | *[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Norovirus Bo/GIII/B309/2003/BEL]] | ||
| + | [[Category: Hansman GS]] | ||
| + | [[Category: Singh BK]] | ||
Current revision
Crystal structure of bovine norovirus P domain
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