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5e9p
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Spirochaeta thermophila X module - CBM64 - wildtype== | |
| + | <StructureSection load='5e9p' size='340' side='right'caption='[[5e9p]], [[Resolution|resolution]] 1.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5e9p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Spirochaeta_thermophila Spirochaeta thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E9P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E9P FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e9p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e9p OCA], [https://pdbe.org/5e9p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e9p RCSB], [https://www.ebi.ac.uk/pdbsum/5e9p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e9p ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/E0RQU0_SPITD E0RQU0_SPITD] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Spirochaeta thermophila secretes seven glycoside hydrolases for plant biomass degradation that carry a carbohydrate-binding module 64 (CBM64) appended at the C-terminus. CBM64 adsorbs to various beta1-4-linked pyranose substrates showing high affinity for cellulose. We present the first crystal structure of a CBM64 at 1.2 A resolution, which reveals a jelly-roll-like fold corresponding to a surface-binding type A CBM. Modeling of its interaction with cellulose indicates that CBM64 achieves association with the hydrophobic face of beta-linked pyranose chains via a unique coplanar arrangement of four exposed tryptophan side chains. This article is protected by copyright. All rights reserved. | ||
| - | + | Structural basis for cellulose binding by the type A carbohydrate-binding module 64 of Spirochaeta thermophila.,Schiefner A, Angelov A, Liebl W, Skerra A Proteins. 2016 Feb 12. doi: 10.1002/prot.25010. PMID:26868291<ref>PMID:26868291</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: Schiefner | + | <div class="pdbe-citations 5e9p" style="background-color:#fffaf0;"></div> |
| - | [[Category: Skerra | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Spirochaeta thermophila]] | ||
| + | [[Category: Schiefner A]] | ||
| + | [[Category: Skerra A]] | ||
Current revision
Spirochaeta thermophila X module - CBM64 - wildtype
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