This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5e9v
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5e9v is ON HOLD Authors: Tallant, C., Hay, D.A., Krojer, T., Nunez-Alonso, G., Picaud, S., Fedorov, O., Schofield, C.J., von Delft, F., Arrowsmith, ...) |
|||
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of BRD9 bromodomain in complex with an indolizine ligand== | |
| + | <StructureSection load='5e9v' size='340' side='right'caption='[[5e9v]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5e9v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E9V FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5L0:1-[1-(IMIDAZO[1,2-A]PYRIDIN-5-YL)-7-(MORPHOLIN-4-YL)INDOLIZIN-3-YL]ETHANONE'>5L0</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e9v OCA], [https://pdbe.org/5e9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e9v RCSB], [https://www.ebi.ac.uk/pdbsum/5e9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e9v ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN] May play a role in chromatin remodeling and regulation of transcription. | ||
| - | + | ==See Also== | |
| - | + | *[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Brennan PE]] |
| - | [[Category: | + | [[Category: Edwards AM]] |
| - | [[Category: | + | [[Category: Fedorov O]] |
| - | [[Category: | + | [[Category: Hay DA]] |
| - | [[Category: | + | [[Category: Knapp S]] |
| - | [[Category: | + | [[Category: Krojer T]] |
| - | [[Category: | + | [[Category: Nunez-Alonso G]] |
| - | [[Category: | + | [[Category: Picaud S]] |
| - | [[Category: | + | [[Category: Schofield CJ]] |
| + | [[Category: Tallant C]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal structure of BRD9 bromodomain in complex with an indolizine ligand
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Brennan PE | Edwards AM | Fedorov O | Hay DA | Knapp S | Krojer T | Nunez-Alonso G | Picaud S | Schofield CJ | Tallant C | Von Delft F
