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2rl2
From Proteopedia
(Difference between revisions)
(New page: 200px {{Structure |PDB= 2rl2 |SIZE=350|CAPTION= <scene name='initialview01'>2rl2</scene>, resolution 2.300Å |SITE= <scene name='pdbsite=AC1:So4+Binding+Site...) |
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| - | [[Image:2rl2.jpg|left|200px]] | ||
| - | + | ==Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine and fosfomycin== | |
| - | + | <StructureSection load='2rl2' size='340' side='right'caption='[[2rl2]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2rl2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_influenzae"_lehmann_and_neumann_1896 "bacterium influenzae" lehmann and neumann 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RL2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GG6:[(1S,2S)-1,2-DIHYDROXYPROPYL]PHOSPHONIC+ACID'>GG6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UD1:URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UD1</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2rl1|2rl1]]</div></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MurA or MurZ ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 "Bacterium influenzae" Lehmann and Neumann 1896])</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rl2 OCA], [https://pdbe.org/2rl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rl2 RCSB], [https://www.ebi.ac.uk/pdbsum/2rl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rl2 ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/MURA_HAEIN MURA_HAEIN]] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rl/2rl2_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rl2 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Enoylpyruvate transferase 3D structures|Enoylpyruvate transferase 3D structures]] | |
| - | + | __TOC__ | |
| - | == | + | </StructureSection> |
| - | + | [[Category: Bacterium influenzae lehmann and neumann 1896]] | |
| - | + | [[Category: Large Structures]] | |
| - | + | ||
| - | + | ||
| - | [[Category: | + | |
| - | [[Category: | + | |
[[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]] | [[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]] | ||
| - | [[Category: Suh, S W | + | [[Category: Suh, S W]] |
| - | [[Category: Yoon, H J | + | [[Category: Yoon, H J]] |
| - | [[Category: | + | [[Category: Cell cycle]] |
| - | [[Category: | + | [[Category: Cell division]] |
| - | [[Category: | + | [[Category: Cell shape]] |
| - | [[Category: | + | [[Category: Cell wall biogenesis/degradation]] |
| - | [[Category: | + | [[Category: Cytoplasm]] |
| - | [[Category: | + | [[Category: Fosfomycin]] |
| - | [[Category: | + | [[Category: Mura]] |
| - | [[Category: | + | [[Category: Murz]] |
| - | [[Category: | + | [[Category: Peptidoglycan synthesis]] |
| - | [[Category: | + | [[Category: Transferase]] |
| - | [[Category: | + | [[Category: Udp-n-acetylglucosamine]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine and fosfomycin
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Categories: Bacterium influenzae lehmann and neumann 1896 | Large Structures | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | Suh, S W | Yoon, H J | Cell cycle | Cell division | Cell shape | Cell wall biogenesis/degradation | Cytoplasm | Fosfomycin | Mura | Murz | Peptidoglycan synthesis | Transferase | Udp-n-acetylglucosamine
