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3x23

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==Radixin complex==
==Radixin complex==
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<StructureSection load='3x23' size='340' side='right' caption='[[3x23]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='3x23' size='340' side='right'caption='[[3x23]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3x23]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X23 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3X23 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3x23]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X23 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3X23 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gc7|1gc7]], [[1j19|1j19]], [[2yvc|2yvc]], [[2ems|2ems]], [[2emt|2emt]], [[2d2q|2d2q]], [[1gc6|1gc6]], [[2d10|2d10]], [[2d11|2d11]], [[1isn|1isn]], [[2zpy|2zpy]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.396&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3x23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x23 OCA], [http://pdbe.org/3x23 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3x23 RCSB], [http://www.ebi.ac.uk/pdbsum/3x23 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3x23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x23 OCA], [https://pdbe.org/3x23 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3x23 RCSB], [https://www.ebi.ac.uk/pdbsum/3x23 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3x23 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RADI_MOUSE RADI_MOUSE]] Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane. [[http://www.uniprot.org/uniprot/MMP14_HUMAN MMP14_HUMAN]] Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15.<ref>PMID:20837484</ref> <ref>PMID:22065321</ref>
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[https://www.uniprot.org/uniprot/RADI_MOUSE RADI_MOUSE] Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3x23" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3x23" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Radixin|Radixin]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aoyama, M]]
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[[Category: Homo sapiens]]
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[[Category: Hakoshima, T]]
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[[Category: Large Structures]]
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[[Category: Kitano, K]]
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[[Category: Mus musculus]]
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[[Category: Mori, T]]
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[[Category: Aoyama M]]
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[[Category: Terawaki, S]]
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[[Category: Hakoshima T]]
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[[Category: Adhesion receptor]]
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[[Category: Kitano K]]
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[[Category: Cell adhesion]]
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[[Category: Mori T]]
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[[Category: Cell invasion]]
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[[Category: Terawaki S]]
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[[Category: Ferm domain]]
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Current revision

Radixin complex

PDB ID 3x23

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