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4woz
From Proteopedia
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==Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine== | ==Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine== | ||
| - | <StructureSection load='4woz' size='340' side='right' caption='[[4woz]], [[Resolution|resolution]] 1.96Å' scene=''> | + | <StructureSection load='4woz' size='340' side='right'caption='[[4woz]], [[Resolution|resolution]] 1.96Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4woz]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WOZ OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4woz]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridioides_difficile Clostridioides difficile]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WOZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WOZ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN9:2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE'>MN9</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4woz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4woz OCA], [https://pdbe.org/4woz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4woz RCSB], [https://www.ebi.ac.uk/pdbsum/4woz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4woz ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/D5Q364_CLODI D5Q364_CLODI] Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.[HAMAP-Rule:MF_01237] |
| + | |||
| + | ==See Also== | ||
| + | *[[N-acetylneuraminate lyase 3D structures|N-acetylneuraminate lyase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Clostridioides difficile]] |
| - | [[Category: Chen | + | [[Category: Large Structures]] |
| - | [[Category: Cui | + | [[Category: Chen X]] |
| - | [[Category: Guo | + | [[Category: Cui YF]] |
| - | [[Category: Liu | + | [[Category: Guo RT]] |
| - | [[Category: Wu | + | [[Category: Liu WD]] |
| - | [[Category: Zhu | + | [[Category: Wu QQ]] |
| - | + | [[Category: Zhu DM]] | |
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| - | + | ||
Current revision
Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine
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Categories: Clostridioides difficile | Large Structures | Chen X | Cui YF | Guo RT | Liu WD | Wu QQ | Zhu DM
