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Azurin

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<StructureSection load='1joi' size='340' side='right' caption='Structure of azurin containing Cu+2 ion (PDB code [[1joi]]).' scene=''>
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<StructureSection load='1joi' size='350' side='right' caption='Structure of azurin containing Cu+2 ion (PDB code [[1joi]]).' scene='59/593967/Cv/1'>
== Function ==
== Function ==
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'''Azurin''' (AZ) is a blue copper protein. AZ mediates electron transfer and contains type I copper center.
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'''Azurin''' (AZ) is a blue copper protein. AZ mediates electron transfer and contains type I copper center.<br />
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For details see [[Intramolecular Electron Transfer in Azurin]].
== Relevance ==
== Relevance ==
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== Structural highlights ==
== Structural highlights ==
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AZ active Cu binding site is shown here. <ref>PMID:8109977</ref>
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<scene name='59/593967/Cv/3'>AZ active Cu binding site is shown here</scene>. <ref>PMID:8109977</ref>
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</StructureSection>
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==3D structures of cAMP-dependent protein kinase==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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*Azurin
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**[[1e65]] – PaAZ – ''Pseudomonas aeruginosa''<br />
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*Cu+2 containing azurin
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**[[1azu]], [[1azr]], [[4azu]], [[5azu]], [[1azn]], [[1cc3]], [[1e5y]], [[1e5z]], [[1jze]], [[2ft6]], [[2ft7]], [[2ft8]], [[2fta]], [[3fs9]], [[3fsa]], [[3fsv]], [[3fsw]], [[3fsz]], [[3ft0]] – PaAZ <br />
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**[[3fq2]], [[4hip]], [[4qkt]] – PaAZ (mutant)<br />
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**[[1cuo]], [[1uat]] – AZ – ''Methylomonas''<br />
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**[[1joi]] – PfAZ – ''Pseudomonas fluorrescens''<br />
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**[[1nwo]] – PpAZ – ''Pseudomonas putida''<br />
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**[[1nwp]] – PpAZ + Zn+2<br />
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**[[2aza]], [[1azb]], [[1azc]], [[1rkr]] – AxAZ – ''Achromobacter xylosoxidans''<br />
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**[[1dyz]], [[1dz0]], [[2ccw]] – AZ II – ''Alcaligenes xylosoxidans''<br />
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**[[2azu]], [[3azu]], [[1ils]], [[1ilu]], [[2tsa]], [[2tsb]], [[1etj]], [[1ag0]], [[1ezl]], [[1jvo]], [[1gr7]], [[1xb3]], [[1xb6]], [[1xb8]], [[2ghz]], [[2hx7]], [[2oj1]], [[3in0]], [[3fpy]], [[3fq1]], [3fq2]], [[3fqy]], [[3in2]], [[3jt2]], [[3jtb]], [[3np3]], [[3np4]], [[3oqr]], [[3n2j]], [[3u25]], [[4hhw]], [[4mfh]], [[4ko5]], [[4ko6]], [[4ko7]], [[4ko9]], [[4kob]], [[4koc]], [[4bww]] – PaAZ (mutant) <br />
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**[[1jvl]], [[2idf]] – PaAZ (mutant) + Ni+2<br />
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**[[1uri]], [[1a4a]], [[1a4b]], [[1a4c]] – AdAZ (mutant) <br />
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**[[2h3x]], [[2h47]], [[2iaa]] – AZ + aromatic amine dehydrogenase – ''Alcaligenes faecalis''<br />
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*Cu+2 containing lanthanide-modified azurin
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**[[1bex]], [[1jzi]], [[1jze]], [[1jzf]], [[1jzj]], [[1jzh]] – PaAZ <br />
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**[[2i7s]], [[2fnw]], [[2i7o]], [[3ibo]], [[4hhg]], [[4k9j]] – PaAZ (mutant) <br />
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*Cu+1 containing azurin
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**[[1jzg]] – PaAZ <br />
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**[[1r1c]], [[2gi0]], [[1i53]], [[2hx8]], [[2hx9]], [[2hxa]], [[2xv0]], [[2xv2]], [[2xv3]] – PaAZ (mutant) <br />
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*Other metals-containing azurin
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**[[1aiz]] – AdAZ + Cd+2 – ''Achromobacter denitrificans'' <br />
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**[[1nzr]] – PaAZ (mutant) + Ni+2 <br />
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**[[1vlx]] – PaAZ + Co+2 <br />
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**[[1e67]] – PaAZ + Zn+2<br />
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**[[2iwe]] – PaAZ (mutant) + Zn+2<br />
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**[[3ay2]] – AZ (mutant) + Zn+2 – ''Neisseria Gonorhoeae''<br />
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**[[3uge]] – PaAZ + Ag+1 <br />
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**[[4hz1]] – PaAZ + Fe+2<br />
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**[[4qlw]] – PaAZ (mutant) + Fe+2<br />
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**[[4jkn]] – PaAZ + Hg+2<br />
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}}
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==3D structures of azurin==
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[[Azurin 3D structures]]
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</StructureSection>

Current revision

Structure of azurin containing Cu+2 ion (PDB code 1joi).

Drag the structure with the mouse to rotate


References

  1. ↑ Zhu DW, Dahms T, Willis K, Szabo AG, Lee X. Crystallization and preliminary crystallographic studies of the crystals of the azurin Pseudomonas fluorescens. Arch Biochem Biophys. 1994 Feb 1;308(2):469-70. PMID:8109977 doi:http://dx.doi.org/10.1006/abbi.1994.1066

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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