This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.




Azurin

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:08, 31 March 2019) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
<StructureSection load='1joi' size='340' side='right' caption='Structure of azurin containing Cu+2 ion (PDB code [[1joi]]).' scene=''>
+
<StructureSection load='1joi' size='350' side='right' caption='Structure of azurin containing Cu+2 ion (PDB code [[1joi]]).' scene='59/593967/Cv/1'>
== Function ==
== Function ==
-
'''Azurin''' (AZ) is a blue copper protein. AZ mediates electron transfer and contains type I copper center.
+
'''Azurin''' (AZ) is a blue copper protein. AZ mediates electron transfer and contains type I copper center.<br />
 +
For details see [[Intramolecular Electron Transfer in Azurin]].
== Relevance ==
== Relevance ==
Line 11: Line 12:
== Structural highlights ==
== Structural highlights ==
-
AZ active Cu binding site is shown here. <ref>PMID:8109977</ref>
+
<scene name='59/593967/Cv/3'>AZ active Cu binding site is shown here</scene>. <ref>PMID:8109977</ref>
-
</StructureSection>
+
-
==3D structures of cAMP-dependent protein kinase==
+
-
 
+
-
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+
-
{{#tree:id=OrganizedByTopic|openlevels=0|
+
-
 
+
-
*Azurin
+
-
 
+
-
**[[1e65]] – PaAZ – ''Pseudomonas aeruginosa''<br />
+
-
 
+
-
*Cu+2 containing azurin
+
-
 
+
-
**[[1azu]], [[1azr]], [[4azu]], [[5azu]], [[1azn]], [[1cc3]], [[1e5y]], [[1e5z]], [[1jze]], [[2ft6]], [[2ft7]], [[2ft8]], [[2fta]], [[3fs9]], [[3fsa]], [[3fsv]], [[3fsw]], [[3fsz]], [[3ft0]] – PaAZ <br />
+
-
**[[3fq2]], [[4hip]], [[4qkt]] – PaAZ (mutant)<br />
+
-
**[[1cuo]], [[1uat]] – AZ – ''Methylomonas''<br />
+
-
**[[1joi]] – PfAZ – ''Pseudomonas fluorrescens''<br />
+
-
**[[1nwo]] – PpAZ – ''Pseudomonas putida''<br />
+
-
**[[1nwp]] – PpAZ + Zn+2<br />
+
-
**[[2aza]], [[1azb]], [[1azc]], [[1rkr]] – AxAZ – ''Achromobacter xylosoxidans''<br />
+
-
**[[1dyz]], [[1dz0]], [[2ccw]] – AZ II – ''Alcaligenes xylosoxidans''<br />
+
-
**[[2azu]], [[3azu]], [[1ils]], [[1ilu]], [[2tsa]], [[2tsb]], [[1etj]], [[1ag0]], [[1ezl]], [[1jvo]], [[1gr7]], [[1xb3]], [[1xb6]], [[1xb8]], [[2ghz]], [[2hx7]], [[2oj1]], [[3in0]], [[3fpy]], [[3fq1]], [3fq2]], [[3fqy]], [[3in2]], [[3jt2]], [[3jtb]], [[3np3]], [[3np4]], [[3oqr]], [[3n2j]], [[3u25]], [[4hhw]], [[4mfh]], [[4ko5]], [[4ko6]], [[4ko7]], [[4ko9]], [[4kob]], [[4koc]], [[4bww]] – PaAZ (mutant) <br />
+
-
**[[1jvl]], [[2idf]] – PaAZ (mutant) + Ni+2<br />
+
-
**[[1uri]], [[1a4a]], [[1a4b]], [[1a4c]] – AdAZ (mutant) <br />
+
-
**[[2h3x]], [[2h47]], [[2iaa]] – AZ + aromatic amine dehydrogenase – ''Alcaligenes faecalis''<br />
+
-
 
+
-
*Cu+2 containing lanthanide-modified azurin
+
-
 
+
-
**[[1bex]], [[1jzi]], [[1jze]], [[1jzf]], [[1jzj]], [[1jzh]] – PaAZ <br />
+
-
**[[2i7s]], [[2fnw]], [[2i7o]], [[3ibo]], [[4hhg]], [[4k9j]] – PaAZ (mutant) <br />
+
-
 
+
-
*Cu+1 containing azurin
+
-
 
+
-
**[[1jzg]] – PaAZ <br />
+
-
**[[1r1c]], [[2gi0]], [[1i53]], [[2hx8]], [[2hx9]], [[2hxa]], [[2xv0]], [[2xv2]], [[2xv3]] – PaAZ (mutant) <br />
+
-
 
+
-
*Other metals-containing azurin
+
-
 
+
-
**[[1aiz]] – AdAZ + Cd+2 – ''Achromobacter denitrificans'' <br />
+
-
**[[1nzr]] – PaAZ (mutant) + Ni+2 <br />
+
-
**[[1vlx]] – PaAZ + Co+2 <br />
+
-
**[[1e67]] – PaAZ + Zn+2<br />
+
-
**[[2iwe]] – PaAZ (mutant) + Zn+2<br />
+
-
**[[3ay2]] – AZ (mutant) + Zn+2 – ''Neisseria Gonorhoeae''<br />
+
-
**[[3uge]] – PaAZ + Ag+1 <br />
+
-
**[[4hz1]] – PaAZ + Fe+2<br />
+
-
**[[4qlw]] – PaAZ (mutant) + Fe+2<br />
+
-
**[[4jkn]] – PaAZ + Hg+2<br />
+
-
 
+
-
}}
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
 +
==3D structures of azurin==
 +
[[Azurin 3D structures]]
 +
</StructureSection>

Current revision

Structure of azurin containing Cu+2 ion (PDB code 1joi).

Drag the structure with the mouse to rotate


References

  1. ↑ Zhu DW, Dahms T, Willis K, Szabo AG, Lee X. Crystallization and preliminary crystallographic studies of the crystals of the azurin Pseudomonas fluorescens. Arch Biochem Biophys. 1994 Feb 1;308(2):469-70. PMID:8109977 doi:http://dx.doi.org/10.1006/abbi.1994.1066

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Retrieved from "http://52.214.119.220/wiki/index.php/Azurin"
Personal tools