Ascorbate peroxidase

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<StructureSection load='1oaf' size='450' side='right' scene='48/486478/Cv/1' caption='Soybean heme-containing ascorbate peroxidase complex with ascorbate and Na+ ion (purple), [[1oaf]]'>
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<StructureSection load='1oaf' size='350' side='right' scene='48/486478/Cv/1' caption='Soybean heme-containing ascorbate peroxidase complex with ascorbate and Na+ ion (purple), [[1oaf]]'>
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__TOC__
== Function ==
== Function ==
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== Structural highlights ==
== Structural highlights ==
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The <scene name='48/486478/Cv/2'>heme-containing active site</scene> of APX contains a His residue (H163 in soybean) which coordinates with the heme and confers stability to the Fe state in the heme.
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The <scene name='48/486478/Cv/4'>heme-containing active site</scene> of APX contains a <scene name='48/486478/Cv/5'>His residue (H163 in soybean) which coordinates with the heme</scene> and confers stability to the Fe state in the heme. <ref>PMID:12640445</ref>
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</StructureSection>
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==3D structures of ascorbate peroxidase==
==3D structures of ascorbate peroxidase==
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[[Ascorbate peroxidase 3D structures]]
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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</StructureSection>
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{{#tree:id=OrganizedByTopic|openlevels=0|
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*Ascorbate peroxidase
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**[[1apx]] – APX – pea<br />
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**[[1oag]], [[2xif]], [[2xih]], [[2xi6]], [[2xj6]] – SoAPX – Soybean<br />
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**[[2cl4]], [[2ggn]], [[2ghc]], [[2ghd]], [[2ghe]], [[2ghk]], [[2ghh]], [[2vnx]], [[2vnz]], [[2vo2]], [[2y6a]], [[2y6b]], [[3zcg]], [[3zch]], [[3zcy]] – SoAPX (mutant)<br />
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**[[1iyn]] – APX – Tobacco<br />
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**[[3riv]] – LmAPX C terminal – ''Leishmania major''<br />
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**[[3riw]] - LmAPX C terminal (mutant)
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*Ascorbate peroxidase binary complex
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**[[1oaf]] – SoAPX + ascorbate <br />
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== References ==
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**[[1v0h]] – SoAPX + salicylhydroxamic acid<br />
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<references/>
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**[[2vcf]] – SoAPX + isoniazid<br />
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**[[2vcn]], [[2vcs]] - SoAPX (mutant) + isoniazid<br />
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**[[2wd4]] - SoAPX (mutant) + biliverdin<br />
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**[[4ged]] – LmAPX + cytochrome c<br />
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}}
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[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Soybean heme-containing ascorbate peroxidase complex with ascorbate and Na+ ion (purple), 1oaf

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References

  1. ↑ Sharp KH, Mewies M, Moody PC, Raven EL. Crystal structure of the ascorbate peroxidase-ascorbate complex. Nat Struct Biol. 2003 Apr;10(4):303-7. PMID:12640445 doi:http://dx.doi.org/10.1038/nsb913

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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