4yjf
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of DAAO(Y228L/R283G) variant (S-methylbenzylamine binding form)== | |
+ | <StructureSection load='4yjf' size='340' side='right'caption='[[4yjf]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[4yjf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YJF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YJF FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=98B:(1S)-1-PHENYLETHANAMINE'>98B</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yjf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yjf OCA], [https://pdbe.org/4yjf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yjf RCSB], [https://www.ebi.ac.uk/pdbsum/4yjf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yjf ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/OXDA_PIG OXDA_PIG] Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. | ||
- | + | ==See Also== | |
- | + | *[[Amino acid oxidase 3D structures|Amino acid oxidase 3D structures]] | |
- | + | __TOC__ | |
- | [[Category: | + | </StructureSection> |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Asano | + | [[Category: Sus scrofa]] |
- | [[Category: | + | [[Category: Asano Y]] |
- | [[Category: | + | [[Category: Ishitsubo E]] |
- | [[Category: | + | [[Category: Kawahara N]] |
- | [[Category: | + | [[Category: Nakano S]] |
+ | [[Category: Tokiwa H]] | ||
+ | [[Category: Yasukawa K]] |
Current revision
Crystal structure of DAAO(Y228L/R283G) variant (S-methylbenzylamine binding form)
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Categories: Large Structures | Sus scrofa | Asano Y | Ishitsubo E | Kawahara N | Nakano S | Tokiwa H | Yasukawa K