5ec4
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5ec4 is ON HOLD until Paper Publication Authors: Gajadeera, C.S., Hou, C., Garneau-Tsodikova, S., Tsodikov, O.V. Description: [[Category: Unreleas...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 13g and CoA== | |
| - | + | <StructureSection load='5ec4' size='340' side='right'caption='[[5ec4]], [[Resolution|resolution]] 2.21Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ec4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EC4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EC4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.21Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5LQ:5-(3-CHLOROPHENYL)-4-METHYL-~{N}-(3-MORPHOLIN-4-YLPROPYL)-1,1-BIS(OXIDANYLIDENE)-1,2-THIAZOL-3-AMINE'>5LQ</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ec4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ec4 OCA], [https://pdbe.org/5ec4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ec4 RCSB], [https://www.ebi.ac.uk/pdbsum/5ec4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ec4 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Garneau-Tsodikova | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Gajadeera CS]] | ||
| + | [[Category: Garneau-Tsodikova S]] | ||
| + | [[Category: Hou C]] | ||
| + | [[Category: Tsodikov OV]] | ||
Current revision
Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 13g and CoA
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