5ejm

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m (Protected "5ejm" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5ejm is ON HOLD
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==ThDP-Mn2+ complex of R413A variant of EcMenD soaked with 2-ketoglutarate for 35 min==
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<StructureSection load='5ejm' size='340' side='right'caption='[[5ejm]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
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Authors: Song, H.G., Dong, C., Chen, Y.Z., Sun, Y.R., Guo, Z.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5ejm]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EJM FirstGlance]. <br>
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Description: ThDP-Mn2+ complex of R413A variant of EcMenD soaked with 2-ketoglutarate for 35 min
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TD5:(4~{R})-4-[3-[(4-AZANYL-2-METHYL-PYRIMIDIN-5-YL)METHYL]-4-METHYL-5-[2-[OXIDANYL(PHOSPHONOOXY)PHOSPHORYL]OXYETHYL]-1,3-THIAZOL-3-IUM-2-YL]-4-OXIDANYL-BUTANOIC+ACID'>TD5</scene></td></tr>
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[[Category: Sun, Y.R]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ejm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ejm OCA], [https://pdbe.org/5ejm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ejm RCSB], [https://www.ebi.ac.uk/pdbsum/5ejm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ejm ProSAT]</span></td></tr>
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[[Category: Guo, Z.H]]
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</table>
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[[Category: Dong, C]]
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== Function ==
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[[Category: Chen, Y.Z]]
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[https://www.uniprot.org/uniprot/MEND_ECOLI MEND_ECOLI] Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).<ref>PMID:1459959</ref> <ref>PMID:17760421</ref>
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[[Category: Song, H.G]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Chen YZ]]
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[[Category: Dong C]]
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[[Category: Guo ZH]]
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[[Category: Song HG]]
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[[Category: Sun YR]]

Current revision

ThDP-Mn2+ complex of R413A variant of EcMenD soaked with 2-ketoglutarate for 35 min

PDB ID 5ejm

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