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5elk

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'''Unreleased structure'''
 
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The entry 5elk is ON HOLD
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==Crystal structure of mouse Unkempt zinc fingers 4-6 (ZnF4-6), bound to RNA==
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<StructureSection load='5elk' size='340' side='right'caption='[[5elk]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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Authors: Teplova, M., Murn, J., Zarnack, K., Shi, Y., Patel, D.S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5elk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ELK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ELK FirstGlance]. <br>
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Description: Crystal structure of mouse Unkempt zinc fingers 4-6 (ZnF4-6), bound to RNA
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Teplova, M]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5elk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5elk OCA], [https://pdbe.org/5elk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5elk RCSB], [https://www.ebi.ac.uk/pdbsum/5elk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5elk ProSAT]</span></td></tr>
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[[Category: Patel, D.S]]
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</table>
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[[Category: Shi, Y]]
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== Function ==
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[[Category: Zarnack, K]]
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[https://www.uniprot.org/uniprot/UNK_MOUSE UNK_MOUSE] Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes (PubMed:25737280).<ref>PMID:25737280</ref>
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[[Category: Murn, J]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Murn J]]
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[[Category: Patel DJ]]
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[[Category: Shi Y]]
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[[Category: Teplova M]]
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[[Category: Zarnack K]]

Current revision

Crystal structure of mouse Unkempt zinc fingers 4-6 (ZnF4-6), bound to RNA

PDB ID 5elk

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