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5esh
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5esh is ON HOLD Authors: Sagatova, A., Keniya, M.V., Wilson, R.K., Sabherwal, M., Tyndall, J.D.A., Monk, B.C. Description: Saccharomyces cerevisiae...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73W mutant in complex with itraconazole== | |
| + | <StructureSection load='5esh' size='340' side='right'caption='[[5esh]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5esh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_YJM789 Saccharomyces cerevisiae YJM789]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ESH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ESH FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1YN:2-[(2R)-BUTAN-2-YL]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZIN-1-YL]PHENYL}-2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONE'>1YN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5esh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5esh OCA], [https://pdbe.org/5esh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5esh RCSB], [https://www.ebi.ac.uk/pdbsum/5esh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5esh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A6ZSR0_YEAS7 A6ZSR0_YEAS7] | ||
| - | + | ==See Also== | |
| - | + | *[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Saccharomyces cerevisiae YJM789]] |
| - | [[Category: | + | [[Category: Keniya MV]] |
| - | [[Category: Sagatova | + | [[Category: Monk BC]] |
| - | [[Category: | + | [[Category: Sabherwal M]] |
| - | [[Category: | + | [[Category: Sagatova A]] |
| + | [[Category: Tyndall JDA]] | ||
| + | [[Category: Wilson RK]] | ||
Current revision
Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73W mutant in complex with itraconazole
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