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2bcp

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==Structural Analysis of Streptococcus pyogenes NADH oxidase: C44S Nox with Azide==
==Structural Analysis of Streptococcus pyogenes NADH oxidase: C44S Nox with Azide==
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<StructureSection load='2bcp' size='340' side='right' caption='[[2bcp]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='2bcp' size='340' side='right'caption='[[2bcp]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2bcp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_scarlatinae"_klein_1884 "micrococcus scarlatinae" klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BCP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2bcp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BCP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1joa|1joa]], [[2bc0|2bc0]], [[2bc1|2bc1]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcp OCA], [http://pdbe.org/2bcp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bcp RCSB], [http://www.ebi.ac.uk/pdbsum/2bcp PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcp OCA], [https://pdbe.org/2bcp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bcp RCSB], [https://www.ebi.ac.uk/pdbsum/2bcp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bcp ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NAOX_STRP6 NAOX_STRP6] Catalyzes the four-electron reduction of molecular oxygen to water.[UniProtKB:P37061]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/2bcp_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/2bcp_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bcp ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Micrococcus scarlatinae klein 1884]]
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[[Category: Large Structures]]
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[[Category: Boles, W H]]
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[[Category: Streptococcus pyogenes]]
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[[Category: Mallett, T C]]
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[[Category: Boles WH]]
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[[Category: Azide]]
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[[Category: Mallett TC]]
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[[Category: Conformational dynamic]]
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[[Category: Cysteine oxidation]]
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[[Category: Flavoprotein]]
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[[Category: Nadh oxidase]]
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[[Category: Oxidoreductase]]
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[[Category: Pyridine nucleotide disulfide oxidoreductase]]
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[[Category: Sulfinic acid]]
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Structural Analysis of Streptococcus pyogenes NADH oxidase: C44S Nox with Azide

PDB ID 2bcp

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