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2mx2

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Current revision (07:02, 1 May 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 2mx2 is ON HOLD until Paper Publication
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==UBX-L domain of VCIP135==
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<StructureSection load='2mx2' size='340' side='right'caption='[[2mx2]]' scene=''>
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Authors: Iwazu, T., Murayama, S., Igarashi, R., Hrioaki, H., Shirakawa, M., Tochio, H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2mx2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MX2 FirstGlance]. <br>
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Description: UBX-L domain of VCIP135
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mx2 OCA], [https://pdbe.org/2mx2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mx2 RCSB], [https://www.ebi.ac.uk/pdbsum/2mx2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mx2 ProSAT]</span></td></tr>
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[[Category: Shirakawa, M]]
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</table>
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[[Category: Murayama, S]]
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== Function ==
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[[Category: Hrioaki, H]]
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[https://www.uniprot.org/uniprot/VCIP1_RAT VCIP1_RAT] Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP. Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.<ref>PMID:12473691</ref> <ref>PMID:15037600</ref>
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[[Category: Iwazu, T]]
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== References ==
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[[Category: Tochio, H]]
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<references/>
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[[Category: Igarashi, R]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Rattus norvegicus]]
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[[Category: Hrioaki H]]
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[[Category: Igarashi R]]
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[[Category: Iwazu T]]
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[[Category: Murayama S]]
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[[Category: Shirakawa M]]
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[[Category: Tochio H]]

Current revision

UBX-L domain of VCIP135

PDB ID 2mx2

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