5ep6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:11, 20 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5ep6 is ON HOLD until Paper Publication
+
==The crystal structure of NAP1 in complex with TBK1==
-
 
+
<StructureSection load='5ep6' size='340' side='right'caption='[[5ep6]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
-
Authors: Li, F., Xie, X., Liu, J., Pan, L.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5ep6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EP6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EP6 FirstGlance]. <br>
-
Description:
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.451&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-
[[Category: Xie, X]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ep6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ep6 OCA], [https://pdbe.org/5ep6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ep6 RCSB], [https://www.ebi.ac.uk/pdbsum/5ep6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ep6 ProSAT]</span></td></tr>
-
[[Category: Pan, L]]
+
</table>
-
[[Category: Li, F]]
+
== Function ==
-
[[Category: Liu, J]]
+
[https://www.uniprot.org/uniprot/AZI2_HUMAN AZI2_HUMAN] Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.<ref>PMID:14560022</ref> <ref>PMID:15611223</ref> <ref>PMID:21931631</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Li F]]
 +
[[Category: Liu J]]
 +
[[Category: Pan L]]
 +
[[Category: Xie X]]

Current revision

The crystal structure of NAP1 in complex with TBK1

PDB ID 5ep6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5ep6"
Personal tools