5eqq
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of HCV NS3/4A WT protease in complex with 5172-Linear (MK-5172 linear analogue)== | |
| + | <StructureSection load='5eqq' size='340' side='right'caption='[[5eqq]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5eqq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EQQ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5RS:~{tert}-butyl+~{N}-[(2~{S})-1-[(2~{S},4~{R})-2-[[(1~{R},2~{R})-1-(cyclopropylsulfonylcarbamoyl)-2-ethyl-cyclopropyl]carbamoyl]-4-(3-ethyl-7-methoxy-quinoxalin-2-yl)oxy-pyrrolidin-1-yl]-3,3-dimethyl-1-oxidanylidene-butan-2-yl]carbamate'>5RS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eqq OCA], [https://pdbe.org/5eqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eqq RCSB], [https://www.ebi.ac.uk/pdbsum/5eqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eqq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/C1KIK8_9HEPC C1KIK8_9HEPC] | ||
| - | + | ==See Also== | |
| - | + | *[[Virus protease 3D structures|Virus protease 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Hepacivirus C]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Ali A]] |
| - | [[Category: | + | [[Category: Aydin C]] |
| - | [[Category: | + | [[Category: Prachanronarong KL]] |
| - | [[Category: | + | [[Category: Schiffer CA]] |
| + | [[Category: Soumana D]] | ||
| + | [[Category: Yilmaz NK]] | ||
Current revision
Crystal structure of HCV NS3/4A WT protease in complex with 5172-Linear (MK-5172 linear analogue)
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