This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1ala

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:31, 7 February 2024) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1ala.jpg|left|200px]]
 
-
{{Structure
+
==STRUCTURE OF CHICKEN ANNEXIN V AT 2.25-ANGSTROMS RESOLUTION==
-
|PDB= 1ala |SIZE=350|CAPTION= <scene name='initialview01'>1ala</scene>, resolution 2.25&Aring;
+
<StructureSection load='1ala' size='340' side='right'caption='[[1ala]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>
+
<table><tr><td colspan='2'>[[1ala]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ALA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ALA FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-
|DOMAIN=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ala FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ala OCA], [https://pdbe.org/1ala PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ala RCSB], [https://www.ebi.ac.uk/pdbsum/1ala PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ala ProSAT]</span></td></tr>
-
|RELATEDENTRY=
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ala FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ala OCA], [http://www.ebi.ac.uk/pdbsum/1ala PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ala RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/ANXA5_CHICK ANXA5_CHICK] Collagen-binding protein.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/al/1ala_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ala ConSurf].
 +
<div style="clear:both"></div>
-
'''STRUCTURE OF CHICKEN ANNEXIN V AT 2.25-ANGSTROMS RESOLUTION'''
+
==See Also==
-
 
+
*[[Annexin 3D structures|Annexin 3D structures]]
-
 
+
__TOC__
-
==Overview==
+
</StructureSection>
-
The crystal structure of chicken annexin V has been solved by molecular replacement and refined at 2.25 A. The final R factor is 19.7% with good geometry. The chicken annexin V structure is very similar to the human annexin V structure, with four similar domains each containing five helices. The structure includes three calcium ions in domains I, II, and IV, each bound by the characteristic K-G-X-G-T-(38 residues)-D/E motif. In view of the structural similarity between human and chicken annexin V, we suggest that they have a common vital function which developed early in evolutionary history.
+
-
 
+
-
==About this Structure==
+
-
1ALA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ALA OCA].
+
-
 
+
-
==Reference==
+
-
Structure of chicken annexin V at 2.25-A resolution., Bewley MC, Boustead CM, Walker JH, Waller DA, Huber R, Biochemistry. 1993 Apr 20;32(15):3923-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8471604 8471604]
+
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Bewley, M C.]]
+
[[Category: Bewley MC]]
-
[[Category: Huber, R.]]
+
[[Category: Huber R]]
-
[[Category: Waller, D A.]]
+
[[Category: Waller DA]]
-
[[Category: calcium/phospholipid-binding protein]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:42:41 2008''
+

Current revision

STRUCTURE OF CHICKEN ANNEXIN V AT 2.25-ANGSTROMS RESOLUTION

PDB ID 1ala

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ala"
Personal tools