5axd
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of mouse SAHH complexed with ribavirin== | |
| - | + | <StructureSection load='5axd' size='340' side='right'caption='[[5axd]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5axd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AXD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=RBV:1-(BETA-D-RIBOFURANOSYL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE'>RBV</scene></td></tr> |
| - | [[Category: Ishihara | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5axd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5axd OCA], [https://pdbe.org/5axd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5axd RCSB], [https://www.ebi.ac.uk/pdbsum/5axd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5axd ProSAT]</span></td></tr> |
| - | [[Category: Kusakabe | + | </table> |
| - | [[Category: Tanaka | + | == Function == |
| + | [https://www.uniprot.org/uniprot/SAHH_MOUSE SAHH_MOUSE] Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Ishihara M]] | ||
| + | [[Category: Kusakabe Y]] | ||
| + | [[Category: Tanaka N]] | ||
Current revision
Crystal structure of mouse SAHH complexed with ribavirin
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