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| - | ==Crystal structure of the mtb phosphoenolpyruvate carboxykinase(pepck) in complex with gdp and metals==
| + | REMOVED: The PDB entry 4rij was removed. |
| - | <StructureSection load='4rij' size='340' side='right' caption='[[4rij]], [[Resolution|resolution]] 2.12Å' scene=''>
| + | |
| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[4rij]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RIJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RIJ FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(GTP) Phosphoenolpyruvate carboxykinase (GTP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.32 4.1.1.32] </span></td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rij OCA], [http://pdbe.org/4rij PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rij RCSB], [http://www.ebi.ac.uk/pdbsum/4rij PDBsum]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/I6Y334_MYCTU I6Y334_MYCTU]] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.[HAMAP-Rule:MF_00452]
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| - | __TOC__
| + | |
| - | </StructureSection>
| + | |
| - | [[Category: Kim, H L]]
| + | |
| - | [[Category: Kriger, I V]]
| + | |
| - | [[Category: Sacchettini, J C]]
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| - | [[Category: Gtp]]
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| - | [[Category: Gtp-dependent pepck]]
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| - | [[Category: Kinase]]
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| - | [[Category: Lyase]]
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| - | [[Category: Metal binding]]
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| - | [[Category: Phosphoryl transfer]]
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| - | [[Category: Rate-limiting gluconeogenic enzyme]]
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