4x3a

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==gallus interleukin-1 beta mutant - R140A==
==gallus interleukin-1 beta mutant - R140A==
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<StructureSection load='4x3a' size='340' side='right' caption='[[4x3a]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='4x3a' size='340' side='right'caption='[[4x3a]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4x3a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X3A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X3A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4x3a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X3A FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x37|4x37]], [[4x38|4x38]], [[4x39|4x39]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x3a OCA], [http://pdbe.org/4x3a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x3a RCSB], [http://www.ebi.ac.uk/pdbsum/4x3a PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x3a OCA], [https://pdbe.org/4x3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x3a RCSB], [https://www.ebi.ac.uk/pdbsum/4x3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x3a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/O73909_CHICK O73909_CHICK]] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753]
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[https://www.uniprot.org/uniprot/O73909_CHICK O73909_CHICK] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753]
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==See Also==
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*[[Interleukin 3D structures|Interleukin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cheng, W T]]
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[[Category: Gallus gallus]]
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[[Category: Yin, H S]]
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[[Category: Large Structures]]
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[[Category: Immune system]]
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[[Category: Cheng WT]]
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[[Category: Yin HS]]

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gallus interleukin-1 beta mutant - R140A

PDB ID 4x3a

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