4pw8
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Human tryptophan 2,3-dioxygenase== | ==Human tryptophan 2,3-dioxygenase== | ||
| - | <StructureSection load='4pw8' size='340' side='right' caption='[[4pw8]], [[Resolution|resolution]] 2.90Å' scene=''> | + | <StructureSection load='4pw8' size='340' side='right'caption='[[4pw8]], [[Resolution|resolution]] 2.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4pw8]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PW8 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4pw8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PW8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PW8 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.902Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pw8 OCA], [https://pdbe.org/4pw8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pw8 RCSB], [https://www.ebi.ac.uk/pdbsum/4pw8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pw8 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/T23O_HUMAN T23O_HUMAN] Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 20: | Line 21: | ||
==See Also== | ==See Also== | ||
| - | *[[Dioxygenase|Dioxygenase]] | + | *[[Dioxygenase 3D structures|Dioxygenase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Ding | + | [[Category: Large Structures]] |
| - | [[Category: Gu | + | [[Category: Ding W]] |
| - | [[Category: Liu | + | [[Category: Gu JH]] |
| - | [[Category: Meng | + | [[Category: Liu ZJ]] |
| - | [[Category: Ouyang | + | [[Category: Meng B]] |
| - | [[Category: Wu | + | [[Category: Ouyang SY]] |
| - | + | [[Category: Wu D]] | |
| - | + | ||
Current revision
Human tryptophan 2,3-dioxygenase
| |||||||||||
Categories: Homo sapiens | Large Structures | Ding W | Gu JH | Liu ZJ | Meng B | Ouyang SY | Wu D
