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5aww
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==Precise Resting State of Thermus thermophilus SecYEG== | ==Precise Resting State of Thermus thermophilus SecYEG== | ||
| - | <StructureSection load='5aww' size='340' side='right' caption='[[5aww]], [[Resolution|resolution]] 2.72Å' scene=''> | + | <StructureSection load='5aww' size='340' side='right'caption='[[5aww]], [[Resolution|resolution]] 2.72Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5aww]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AWW OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5aww]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AWW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AWW FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.724Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aww OCA], [https://pdbe.org/5aww PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aww RCSB], [https://www.ebi.ac.uk/pdbsum/5aww PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aww ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/SECY_THET8 SECY_THET8] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Ishitani | + | [[Category: Large Structures]] |
| - | [[Category: Kumazaki | + | [[Category: Thermus thermophilus HB8]] |
| - | [[Category: Kusakizako | + | [[Category: Ishitani R]] |
| - | [[Category: Nureki | + | [[Category: Kumazaki K]] |
| - | [[Category: Sugano | + | [[Category: Kusakizako T]] |
| - | [[Category: Takemoto | + | [[Category: Nureki O]] |
| - | [[Category: Tanaka | + | [[Category: Sugano Y]] |
| - | [[Category: Tsukazaki | + | [[Category: Takemoto M]] |
| - | + | [[Category: Tanaka Y]] | |
| - | + | [[Category: Tsukazaki T]] | |
| - | + | ||
Current revision
Precise Resting State of Thermus thermophilus SecYEG
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