5ayl

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:51, 8 November 2023) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5ayl is ON HOLD until Paper Publication
+
==Crystal structure of ERdj5 form II==
 +
<StructureSection load='5ayl' size='340' side='right'caption='[[5ayl]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[5ayl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AYL FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PS:3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE'>1PS</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ayl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ayl OCA], [https://pdbe.org/5ayl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ayl RCSB], [https://www.ebi.ac.uk/pdbsum/5ayl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ayl ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DJC10_MOUSE DJC10_MOUSE] Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.<ref>PMID:12411443</ref> <ref>PMID:12446677</ref> <ref>PMID:18653895</ref> <ref>PMID:21329881</ref>
-
Authors: Watanabe, S., Maegawa, K., Inaba, K.
+
==See Also==
-
 
+
*[[DnaJ homolog 3D structures|DnaJ homolog 3D structures]]
-
Description: Crystal structure of ERdj5 form II
+
== References ==
-
[[Category: Unreleased Structures]]
+
<references/>
-
[[Category: Inaba, K]]
+
__TOC__
-
[[Category: Watanabe, S]]
+
</StructureSection>
-
[[Category: Maegawa, K]]
+
[[Category: Large Structures]]
 +
[[Category: Mus musculus]]
 +
[[Category: Inaba K]]
 +
[[Category: Maegawa K]]
 +
[[Category: Watanabe S]]

Current revision

Crystal structure of ERdj5 form II

PDB ID 5ayl

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5ayl"
Personal tools