5bzo
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule== | |
| + | <StructureSection load='5bzo' size='340' side='right'caption='[[5bzo]], [[Resolution|resolution]] 1.22Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5bzo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BZO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.22Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4XC:3-(8-AMINO-3,4-DIHYDROISOQUINOLIN-2(1H)-YL)-N-METHYLPROPANAMIDE'>4XC</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bzo OCA], [https://pdbe.org/5bzo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bzo RCSB], [https://www.ebi.ac.uk/pdbsum/5bzo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bzo ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing. | ||
| - | + | ==See Also== | |
| - | + | *[[CD44|CD44]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Finzel | + | [[Category: Large Structures]] |
| - | [[Category: Liu | + | [[Category: Mus musculus]] |
| + | [[Category: Finzel BC]] | ||
| + | [[Category: Liu LK]] | ||
Current revision
Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
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