5dlo
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==S. aureus MazF in complex with substrate analogue== | |
| - | + | <StructureSection load='5dlo' size='340' side='right'caption='[[5dlo]], [[Resolution|resolution]] 1.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5dlo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DLO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DLO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.401Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| - | [[Category: Loris | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dlo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dlo OCA], [https://pdbe.org/5dlo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dlo RCSB], [https://www.ebi.ac.uk/pdbsum/5dlo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dlo ProSAT]</span></td></tr> |
| - | [[Category: Zorzini | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MAZF_STAA8 MAZF_STAA8] Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA. Neutralized by coexpression with cognate antitoxin MazE.[UniProtKB:A6QIR4] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia phage MS2]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staphylococcus aureus]] | ||
| + | [[Category: Loris R]] | ||
| + | [[Category: Zorzini V]] | ||
Current revision
S. aureus MazF in complex with substrate analogue
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