This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5dxy
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Dbr2== | |
| - | + | <StructureSection load='5dxy' size='340' side='right'caption='[[5dxy]], [[Resolution|resolution]] 1.77Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5dxy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Artemisia_annua Artemisia annua]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DXY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5J8:[[(2R,3S,4R,5R)-5-(5-aminocarbonyl-3,4-dihydro-2H-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methyl+hydrogen+phosphate'>5J8</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dxy OCA], [https://pdbe.org/5dxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dxy RCSB], [https://www.ebi.ac.uk/pdbsum/5dxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dxy ProSAT]</span></td></tr> |
| - | [[Category: Chen | + | </table> |
| - | [[Category: Xu | + | == Function == |
| + | [https://www.uniprot.org/uniprot/DBR2_ARTAN DBR2_ARTAN] Involved in the biosynthesis of the antimalarial endoperoxide artemisinin by catalyzing the double bond reduction of (11R)-dihydroartemisinic aldehyde to produce artemisinic aldehyde. Also able to reduce artemisinic alcohol and artemisinic acid to a lesser extent.<ref>PMID:18495659</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Artemisia annua]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen TT]] | ||
| + | [[Category: Li L]] | ||
| + | [[Category: Xu YC]] | ||
Current revision
Crystal structure of Dbr2
| |||||||||||
