5dxy

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'''Unreleased structure'''
 
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The entry 5dxy is ON HOLD until Paper Publication
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==Crystal structure of Dbr2==
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<StructureSection load='5dxy' size='340' side='right'caption='[[5dxy]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
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Authors: Li, L., Chen, T.T., Xu, Y.C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5dxy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Artemisia_annua Artemisia annua]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DXY FirstGlance]. <br>
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Description: Crystal structure of Dbr2
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5J8:[[(2R,3S,4R,5R)-5-(5-aminocarbonyl-3,4-dihydro-2H-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methyl+hydrogen+phosphate'>5J8</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
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[[Category: Li, L]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dxy OCA], [https://pdbe.org/5dxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dxy RCSB], [https://www.ebi.ac.uk/pdbsum/5dxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dxy ProSAT]</span></td></tr>
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[[Category: Chen, T.T]]
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</table>
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[[Category: Xu, Y.C]]
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== Function ==
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[https://www.uniprot.org/uniprot/DBR2_ARTAN DBR2_ARTAN] Involved in the biosynthesis of the antimalarial endoperoxide artemisinin by catalyzing the double bond reduction of (11R)-dihydroartemisinic aldehyde to produce artemisinic aldehyde. Also able to reduce artemisinic alcohol and artemisinic acid to a lesser extent.<ref>PMID:18495659</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Artemisia annua]]
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[[Category: Large Structures]]
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[[Category: Chen TT]]
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[[Category: Li L]]
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[[Category: Xu YC]]

Current revision

Crystal structure of Dbr2

PDB ID 5dxy

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