5e5l
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 1 at 1.89 Angstrom== | |
| - | + | <StructureSection load='5e5l' size='340' side='right'caption='[[5e5l]], [[Resolution|resolution]] 1.89Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5e5l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E5L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E5L FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e5l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e5l OCA], [https://pdbe.org/5e5l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e5l RCSB], [https://www.ebi.ac.uk/pdbsum/5e5l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e5l ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Ginell | + | == Function == |
| - | [[Category: Lamichhane | + | [https://www.uniprot.org/uniprot/LDT1_MYCTU LDT1_MYCTU] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is thought to play a role in adaptation to the nonreplicative state of M.tuberculosis.<ref>PMID:18408028</ref> <ref>PMID:24041897</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Ginell SL]] | ||
| + | [[Category: Kumar P]] | ||
| + | [[Category: Lamichhane G]] | ||
Current revision
Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 1 at 1.89 Angstrom
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