5ezk

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==RNA polymerase model placed by Molecular replacement into X-ray diffraction map of DNA-bound RNA Polymerase-Sigma 54 holoenzyme complex.==
==RNA polymerase model placed by Molecular replacement into X-ray diffraction map of DNA-bound RNA Polymerase-Sigma 54 holoenzyme complex.==
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<StructureSection load='5ezk' size='340' side='right' caption='[[5ezk]], [[Resolution|resolution]] 8.50&Aring;' scene=''>
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<StructureSection load='5ezk' size='340' side='right'caption='[[5ezk]], [[Resolution|resolution]] 8.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ezk]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EZK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EZK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ezk]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EZK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EZK FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 8.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ezk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ezk OCA], [http://pdbe.org/5ezk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ezk RCSB], [http://www.ebi.ac.uk/pdbsum/5ezk PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ezk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ezk OCA], [https://pdbe.org/5ezk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ezk RCSB], [https://www.ebi.ac.uk/pdbsum/5ezk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ezk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RPOZ_ECOLI RPOZ_ECOLI]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.[HAMAP-Rule:MF_00366] [[http://www.uniprot.org/uniprot/RPOA_ECO57 RPOA_ECO57]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. [[http://www.uniprot.org/uniprot/RPOC_ECO57 RPOC_ECO57]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. [[http://www.uniprot.org/uniprot/RPOB_ECO57 RPOB_ECO57]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
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[https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: DNA-directed RNA polymerase]]
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[[Category: Escherichia coli]]
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[[Category: Buck, M]]
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[[Category: Large Structures]]
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[[Category: Darbari, V C]]
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[[Category: Buck M]]
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[[Category: Glyde, R]]
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[[Category: Darbari VC]]
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[[Category: Lu, D]]
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[[Category: Glyde R]]
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[[Category: Murakami, K S]]
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[[Category: Lu D]]
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[[Category: Wang, Y]]
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[[Category: Murakami KS]]
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[[Category: Yang, Y]]
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[[Category: Wang Y]]
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[[Category: Zhang, N]]
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[[Category: Yang Y]]
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[[Category: Zhang, X]]
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[[Category: Zhang N]]
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[[Category: Rna polymerase]]
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[[Category: Zhang X]]
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[[Category: Transferase]]
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Current revision

RNA polymerase model placed by Molecular replacement into X-ray diffraction map of DNA-bound RNA Polymerase-Sigma 54 holoenzyme complex.

PDB ID 5ezk

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