5fct
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5fct is ON HOLD until Paper Publication Authors: Dowiercial, A., Wilk, P., Jarmula, A., Rode, W. Description: Mouse thymidylate synthase in ternary...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Mouse thymidylate synthase in ternary complex with FdUMP and methylenetetrahydrofolate.== | |
| + | <StructureSection load='5fct' size='340' side='right'caption='[[5fct]], [[Resolution|resolution]] 1.55Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5fct]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FCT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FCT FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C2F:5-METHYL-5,6,7,8-TETRAHYDROFOLIC+ACID'>C2F</scene>, <scene name='pdbligand=UFP:5-FLUORO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>UFP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fct FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fct OCA], [https://pdbe.org/5fct PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fct RCSB], [https://www.ebi.ac.uk/pdbsum/5fct PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fct ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Dowiercial | + | [[Category: Mus musculus]] |
| - | [[Category: Rode | + | [[Category: Dowiercial A]] |
| - | [[Category: | + | [[Category: Jarmula A]] |
| + | [[Category: Rode W]] | ||
| + | [[Category: Wilk P]] | ||
Current revision
Mouse thymidylate synthase in ternary complex with FdUMP and methylenetetrahydrofolate.
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