5f71

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'''Unreleased structure'''
 
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The entry 5f71 is ON HOLD until Paper Publication
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==Human T-cell immunoglobulin and mucin domain protein 3 (hTIM-3)==
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<StructureSection load='5f71' size='340' side='right'caption='[[5f71]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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Authors: Gao, G.F., Lu, G., Wang, H., Qi, J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5f71]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F71 FirstGlance]. <br>
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Description: Human T-cell immunoglobulin and mucin domain protein 3 (hTIM-3)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.404&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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[[Category: Gao, G.F]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f71 OCA], [https://pdbe.org/5f71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f71 RCSB], [https://www.ebi.ac.uk/pdbsum/5f71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f71 ProSAT]</span></td></tr>
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[[Category: Lu, G]]
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</table>
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[[Category: Wang, H]]
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== Function ==
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[[Category: Qi, J]]
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[https://www.uniprot.org/uniprot/HAVR2_HUMAN HAVR2_HUMAN] Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.<ref>PMID:14556005</ref> <ref>PMID:16286920</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Gao GF]]
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[[Category: Lu G]]
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[[Category: Qi J]]
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[[Category: Wang H]]

Current revision

Human T-cell immunoglobulin and mucin domain protein 3 (hTIM-3)

PDB ID 5f71

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