DnaC helicase loader
From Proteopedia
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| - | + | <StructureSection load='2vye' size='350' side='right' scene='48/483919/Cv/1' caption='DnaC helicase loader hexamer complex with DNA [[2vye]]'> | |
| - | '''DnaC helicase loader''' (DnaC) transfers helicase to replication origins. The helicase loaders belong to two classes. The ‘'''ring breakers'''’ break the hexameric helicase to allow the DNA to pass through. The ‘'''ring makers'''’ assemble the helicase monomers to hexamers around the DNA.<ref>PMID:23562643</ref> | + | |
| + | '''DnaC helicase loader''' (DnaC) transfers helicase to replication origins. The helicase loaders belong to two classes. The ‘'''ring breakers'''’ break the hexameric helicase to allow the DNA to pass through. The ‘'''ring makers'''’ assemble the helicase monomers to <scene name='48/483919/Cv/2'>hexamers around the DNA</scene>.<ref>PMID:23562643</ref> | ||
For the theoretical model structure of E. coli DnaC see [[Structure of E. coli DnaC helicase loader]]. | For the theoretical model structure of E. coli DnaC see [[Structure of E. coli DnaC helicase loader]]. | ||
| - | < | + | </StructureSection> |
== 3D Structures of DnaC helicase loader == | == 3D Structures of DnaC helicase loader == | ||
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[[3ecc]] – AaDnaC + ADP-BeF3<br /> | [[3ecc]] – AaDnaC + ADP-BeF3<br /> | ||
[[2vye]] – GkDnaC + DNA – ''Geobacillus kaustophilus''<br /> | [[2vye]] – GkDnaC + DNA – ''Geobacillus kaustophilus''<br /> | ||
| - | [[2vyf]] – GkDnaC | + | [[2vyf]] – GkDnaC<br /> |
| + | [[6qel]] – EcDnaC + BnaB + ADP – ''Escherichia coli'' – Cryo EM<br /> | ||
| + | [[6kza]] – EcDnaC N-terminal 1-56 + BnaB C-terminal 180-471<br /> | ||
| + | [[6qem]] – EcDnaC + BnaB + DNA + ADP – Cryo EM<br /> | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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3D Structures of DnaC helicase loader
Updated on 06-July-2021
3ec2 – AaDnaC – Aquifex aeolicus
3ecc – AaDnaC + ADP-BeF3
2vye – GkDnaC + DNA – Geobacillus kaustophilus
2vyf – GkDnaC
6qel – EcDnaC + BnaB + ADP – Escherichia coli – Cryo EM
6kza – EcDnaC N-terminal 1-56 + BnaB C-terminal 180-471
6qem – EcDnaC + BnaB + DNA + ADP – Cryo EM
References
- ↑ Arias-Palomo E, O'Shea VL, Hood IV, Berger JM. The bacterial DnaC helicase loader is a DnaB ring breaker. Cell. 2013 Apr 11;153(2):438-48. doi: 10.1016/j.cell.2013.03.006. Epub 2013 Apr, 4. PMID:23562643 doi:http://dx.doi.org/10.1016/j.cell.2013.03.006
