Bungarotoxin

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:21, 18 April 2019) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
<StructureSection load='1hc9' size='450' side='right' scene='42/423360/Cv/2' caption='α-Bungarotoxin (green) complex with peptide derived from acetylcholine receptor (yellow) and I- ion (PDB code [[1hc9]])'>
+
<StructureSection load='1hc9' size='450' side='right' scene='42/423360/Cv/5' caption='α-Bungarotoxin (green) complex with peptide derived from acetylcholine receptor (yellow) and I- ion (PDB code [[1hc9]])'>
[[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait.<br />
[[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait.<br />
* '''α-BGT''' binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in [[Alpha-bungarotoxin]].<br />
* '''α-BGT''' binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in [[Alpha-bungarotoxin]].<br />
Line 7: Line 7:
For toxins in Proteopedia see [[Toxins]].
For toxins in Proteopedia see [[Toxins]].
-
<scene name='42/423360/Cv/3'>Iod coordination site</scene> in α-Bungarotoxin (PDB code [[1hc9]]).<ref>PMID:11683996</ref>
+
<scene name='42/423360/Cv/4'>Iod coordination site</scene> in α-Bungarotoxin (PDB code [[1hc9]]).<ref>PMID:11683996</ref> Water molecule shown as red sphere.
-
</StructureSection>
+
 
== 3D Structures of Bungarotoxin ==
== 3D Structures of Bungarotoxin ==
-
+
[[Bungarotoxin 3D structures]]
-
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+
-
{{#tree:id=OrganizedByTopic|openlevels=0|
+
-
* Bungarotoxin
+
</StructureSection>
-
 
+
-
**[[2abx]] – α-BGT <br />
+
-
**[[1kfh]], [[1ik8]], [[1ikc]], [[1idi]], [[1idl]], [[2nbt]] – α−BGT – NMR<br />
+
-
**[[1bun]] - β2-BGT<br />
+
-
**[[1mr6]] – γ-BGT – NMR<br />
+
-
**[[1kba]] – κ-BGT<br />
+
-
 
+
-
* BGT+binding peptide
+
-
 
+
-
**[[1l4w]], [[1ljz]], [[1kc4]], [[1kl8]], [[1jbd]], [[1haa]], [[1haj]], [[1idg]], [[1idh]], [[1hoy]], [[1bxp]], [[1abt]], [[1rgj]], [[2btx]] – α-BGT+AChR peptide - NMR<br />
+
-
**[[1hc9]] - α-BGT+AChR peptide<br />
+
-
 
+
-
* BGT+ AChR subunit
+
-
**[[2qc1]] – α-BGT+mAChR α subunit <br />
 
-
**[[4hqp]] - α−BGT+ AChR α7 subunit<br />
 
-
**[[4uy2]] - α−BGT+ AChR α9 subunit<br />
 
-
}}
 
== References ==
== References ==
<references/>
<references/>

Current revision

α-Bungarotoxin (green) complex with peptide derived from acetylcholine receptor (yellow) and I- ion (PDB code 1hc9)

Drag the structure with the mouse to rotate

References

  1. ↑ Harel M, Kasher R, Nicolas A, Guss JM, Balass M, Fridkin M, Smit AB, Brejc K, Sixma TK, Katchalski-Katzir E, Sussman JL, Fuchs S. The binding site of acetylcholine receptor as visualized in the X-Ray structure of a complex between alpha-bungarotoxin and a mimotope peptide. Neuron. 2001 Oct 25;32(2):265-75. PMID:11683996

Alpha-bungarotoxin

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky

Retrieved from "http://52.214.119.220/wiki/index.php/Bungarotoxin"
Personal tools