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5hdn
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of heat shock factor1-DBD complex with ds-DNA and TtT== | |
| + | <StructureSection load='5hdn' size='340' side='right'caption='[[5hdn]], [[Resolution|resolution]] 1.68Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5hdn]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HDN FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.68Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hdn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hdn OCA], [https://pdbe.org/5hdn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hdn RCSB], [https://www.ebi.ac.uk/pdbsum/5hdn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hdn ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HSF1_HUMAN HSF1_HUMAN] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.<ref>PMID:11447121</ref> <ref>PMID:8946918</ref> <ref>PMID:9121459</ref> <ref>PMID:9535852</ref> <ref>PMID:11583998</ref> <ref>PMID:12659875</ref> <ref>PMID:12665592</ref> <ref>PMID:16278218</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Heat shock factor|Heat shock factor]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Feng H]] | ||
| + | [[Category: Liu W]] | ||
| + | [[Category: Wang DC]] | ||
Current revision
Crystal structure of heat shock factor1-DBD complex with ds-DNA and TtT
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Categories: Homo sapiens | Large Structures | Feng H | Liu W | Wang DC
