Ceruloplasmin
From Proteopedia
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CP mutation causes the autosomal recessive disorder - Aceruloplasminemia which results in accumulation of iron in the brain. | CP mutation causes the autosomal recessive disorder - Aceruloplasminemia which results in accumulation of iron in the brain. | ||
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| + | == Structural highlights == | ||
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| + | <scene name='46/467272/Cv/8'>Cu-O-Cu coordination site</scene> and | ||
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| + | <scene name='46/467272/Cv/9'>Cu-O coordination site</scene> in human ceruloplasmin (PDB entry [[1kcw]]). | ||
</StructureSection> | </StructureSection> | ||
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[[1kcw]], [[2j5w]], [[4enz]] – hCP - human<br /> | [[1kcw]], [[2j5w]], [[4enz]] – hCP - human<br /> | ||
[[4ejx]] – hCP + myeloperoxidase<br /> | [[4ejx]] – hCP + myeloperoxidase<br /> | ||
| + | [[5n0k]], [[5n4l]] – CP – rat<br /> | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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3D structures of ceruloplasmin
Updated on 11-February-2019
1kcw, 2j5w, 4enz – hCP - human
4ejx – hCP + myeloperoxidase
5n0k, 5n4l – CP – rat
References
- ↑ Hellman NE, Gitlin JD. Ceruloplasmin metabolism and function. Annu Rev Nutr. 2002;22:439-58. Epub 2002 Apr 4. PMID:12055353 doi:http://dx.doi.org/10.1146/annurev.nutr.22.012502.114457
