5d5w

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==Crystal structure of Chaetomium thermophilum Skn7 with HSE DNA==
==Crystal structure of Chaetomium thermophilum Skn7 with HSE DNA==
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<StructureSection load='5d5w' size='340' side='right' caption='[[5d5w]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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<StructureSection load='5d5w' size='340' side='right'caption='[[5d5w]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5d5w]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D5W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D5W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5d5w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum_var._thermophilum_DSM_1495 Chaetomium thermophilum var. thermophilum DSM 1495] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D5W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5D5W FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d5w OCA], [http://pdbe.org/5d5w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d5w RCSB], [http://www.ebi.ac.uk/pdbsum/5d5w PDBsum]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5d5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d5w OCA], [https://pdbe.org/5d5w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5d5w RCSB], [https://www.ebi.ac.uk/pdbsum/5d5w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5d5w ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SKN7_CHATD SKN7_CHATD] Transcription factor that is part of a SLN1-YPD1-SKN7 two-component regulatory system, which controls gene expression in response to changes in the osmolarity of the extracellular environment. Under low osmotic conditions, phosphorylated and activated by the phosphorelay intermediate protein YPD1. Also activated in response to oxidative stress, independent on the two-component regulatory system. Regulates heat shock genes in response to oxidative stress and genes involved in cell wall integrity in response to osmotic changes.[UniProtKB:P38889]
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bracher, A]]
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[[Category: Chaetomium thermophilum var. thermophilum DSM 1495]]
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[[Category: Hartl, F U]]
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[[Category: Homo sapiens]]
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[[Category: Hayer-Hartl, M]]
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[[Category: Large Structures]]
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[[Category: Neudegger, T]]
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[[Category: Bracher A]]
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[[Category: Verghese, J]]
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[[Category: Hartl FU]]
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[[Category: Double helix]]
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[[Category: Hayer-Hartl M]]
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[[Category: Helix-turn-helix]]
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[[Category: Neudegger T]]
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[[Category: Protein-dna complex]]
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[[Category: Verghese J]]
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[[Category: Transcription]]
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Current revision

Crystal structure of Chaetomium thermophilum Skn7 with HSE DNA

PDB ID 5d5w

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