4d4k
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==human PFKFB3 in complex with a pyrrolopyrimidone compound== | ==human PFKFB3 in complex with a pyrrolopyrimidone compound== | ||
| - | <StructureSection load='4d4k' size='340' side='right' caption='[[4d4k]], [[Resolution|resolution]] 3.24Å' scene=''> | + | <StructureSection load='4d4k' size='340' side='right'caption='[[4d4k]], [[Resolution|resolution]] 3.24Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4d4k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D4K OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4d4k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D4K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D4K FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BKE:7-(4-METHOXYPHENYL)-5-PHENYL-3,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-ONE'>BKE</scene>, <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.24Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BKE:7-(4-METHOXYPHENYL)-5-PHENYL-3,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-ONE'>BKE</scene>, <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d4k OCA], [https://pdbe.org/4d4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d4k RCSB], [https://www.ebi.ac.uk/pdbsum/4d4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d4k ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/F263_HUMAN F263_HUMAN] Synthesis and degradation of fructose 2,6-bisphosphate. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Bennett | + | [[Category: Homo sapiens]] |
| - | [[Category: Critchlow | + | [[Category: Large Structures]] |
| - | [[Category: Davies | + | [[Category: Bennett N]] |
| - | [[Category: Debreczeni | + | [[Category: Critchlow S]] |
| - | [[Category: Evans | + | [[Category: Davies G]] |
| - | [[Category: Holdgate | + | [[Category: Debreczeni JE]] |
| - | [[Category: Jones | + | [[Category: Evans N]] |
| - | [[Category: Leach | + | [[Category: Holdgate G]] |
| - | [[Category: Maman | + | [[Category: Jones NP]] |
| - | [[Category: McLoughlin | + | [[Category: Leach L]] |
| - | [[Category: Preston | + | [[Category: Maman S]] |
| - | [[Category: Rigoreau | + | [[Category: McLoughlin S]] |
| - | [[Category: Stgallay | + | [[Category: Preston M]] |
| - | [[Category: Thomas | + | [[Category: Rigoreau L]] |
| - | [[Category: Walker | + | [[Category: Stgallay SA]] |
| - | [[Category: Walsch | + | [[Category: Thomas A]] |
| - | [[Category: Ward | + | [[Category: Walker G]] |
| - | [[Category: Wheatley | + | [[Category: Walsch J]] |
| - | [[Category: Winter | + | [[Category: Ward RA]] |
| - | + | [[Category: Wheatley E]] | |
| - | + | [[Category: Winter J]] | |
| - | + | ||
| - | + | ||
Current revision
human PFKFB3 in complex with a pyrrolopyrimidone compound
| |||||||||||
Categories: Homo sapiens | Large Structures | Bennett N | Critchlow S | Davies G | Debreczeni JE | Evans N | Holdgate G | Jones NP | Leach L | Maman S | McLoughlin S | Preston M | Rigoreau L | Stgallay SA | Thomas A | Walker G | Walsch J | Ward RA | Wheatley E | Winter J
